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Old 12-26-2018, 04:53 AM   #1
Paracelsus
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Default depression resistant approaches

recommendations or food for thought for treatment resistant axiety/depressive sufferers

many SSRIs can be started at 2.5 mg easily with cutting in half a 5mg tablets (usually the smallest manufactured dose). zoloft 25 mg (50 mg lowest tablets)
liquid titrations can work if your using the right SSRI and the right juice. not attempt this unless you do your own research.

antipsychotics can cause akathisia and that's a big problem if your only using it for sleep or anxiety/depression without psychosis history. if you don't get akathisia that this may not apply to you. (use benadryl if your currently experiancing internal restlessness) if necessary find the correct antipsychotic for your individual body. top recommended for adhd depression meltdowns risperadone.

alt sleep aids quetiapine, benadryl (buy generic diphenhydramine HCl it's cheaper), melatonin (use repetitively) magnesium citrate, lithium orotate

lunesta, ambien, temazapam and other benzos are prescription options
kava kava, kratom and other natural remedies not fda approved may have drug drug interactions and always talk to doctor. cbd without tch appears safe

lithium carbonate. the literature urges psychs to prescribe near toxic doses which increase side effect profile. it's arguable if the additional benefit are worth it. subtheraputic doses of lithium may work as adjunct to depressives with adhd.

nootropics not rerecorded unless talk to provider prior

stimulants: guanfacine works well in combonation for people needing to take adderall or dexedrine. ssris may may also decrease negetive side effects of stimulents.

getting off benzodiazapines for dry out periods (when your not being economically productive) liquid titration works depending on your solvent(s). also just cutting the pills into smaller pieces works as well.

microdosing: not reliable enough data in scientific literature and in the 'no fly zone' as research continues to pave new insights. anecdotal testimonies exist for exceptionally unique cases. have patience as new fda studies come to surface. don't resort to street quality pharmacuticals or drugs as no1s situation is worth the careless risks associated with it. these could be potentially great in some applications but not all by any means.

managing depressive episodes and suicidal thoughts: focus on the sublime in nature.

feel free to share additional insights to help those that are treatment resistant.
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Old 01-04-2019, 10:05 AM   #2
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Default Re: depression resistant approaches

Thanks. I wish I knew more to help.
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Old 01-07-2019, 11:50 PM   #3
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Default Re: depression resistant approaches

Gabapentin can ameliorate akathisia caused by antipsychotics and so can Atarax. Both have very mild side effects profiles and both improve sleep.
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past medications: Depakote, Lamictal, Lithium, Seroquel, Trazodone, Risperdal, Cogentin, Remerol, Prozac, Amitriptyline, Ambien, Lorazepam, Klonopin, Saphris, Trileptal, Clozapine and Clozapine+Wellbutrin
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Old 01-08-2019, 05:59 AM   #4
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Default Re: depression resistant approaches

aspiringauthor: that's very interesting. i have not heard of gabapentin used for akathisia. hydroxazine or atarax are limited in what they can do for akathisia. i know for certain that the 1st gen antipsychotics are not alleviated by hydroxyzine, but there are antiparkinson medications that are worth looking into.

a good way to be an advocate for your own mental health is to look up the classes of pharmaceutical drugs used in psychiatry. there are also many add ons that are definitely important to research, because mental illness is a complex disorder in multiple parts of the brain. one drug usually only does one angle. you need multiple angles for debilitating illness
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Old 01-14-2019, 02:36 PM   #5
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Default Re: depression resistant approaches

gabapentin is the non-addictive poor man's valium (For me...) when it comes to dealing with life and also treatment with an 'atypical' neuroleptic.

there are a number of rx drug options for the 'treatment resistant'...effexor+remeron, add buspar, add a stimulant, add low dose lithium, add one of the nicer atypicals (abilify, seroquel), switch to a tca...

benzodiazepines can both cause and exacerbate depression, but xanax was once used in lieu of antidepressants in some people, some times. i think the current rule is try not to go above 4mgs/day. klonopin is notorious for dampening mood, but its now the It mother's little helper. go figure.

wellbutrin. now and then an maoi. check for any number of physical ailments (thyroid seems to be a big one). add psychotherapy. exercise. bright light therapy. and of course...

electroshock. id say steer clear, but some people swear by it. rarely, brain operations (psychosurgery) still happen. i read an account by one lady, she was given an operation (not a full on lobotomy) in the UK, for intractable depression. she's happy. then again...once you've been operated on, i suppose you make your peace with it or go crazy.

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Old 01-15-2019, 04:40 AM   #6
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Default Re: depression resistant approaches

Some people have success with stimulants like adderall for severe treatment resistant depression.
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Old 01-15-2019, 07:06 AM   #7
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Default Re: depression resistant approaches

I've found Abilify, an antipsychotic, to help my depression a bit, but antidepressants haven't touched it.
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