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Vaniqa (eflornithine)

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Generic name: Eflornithine


Eflornithine ( ee–FLOOR–nith–een) is used to slow down bodily substances called enzymes that help hair grow. The effect is slower facial hair growth.

This medicine is available only with your doctor's prescription, in the following dosage form:

  • Cream (U.S.)

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For eflornithine, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to eflornithine. Also tell your health care professional if you are allergic to any other substances or topical medications.

Pregnancy—Studies with eflornithine have not been done in pregnant women. In animal studies, when taken by mouth, eflornithine has been shown to cause birth defects or other problems. If you are pregnant or plan to become pregnant, discuss with your doctor whether you should use this medicine during pregnancy.

Breast-feeding—It is not known whether eflornithine passes into breast milk. Mothers who are taking this medicine and wish to breast–feed should discuss this with their doctor.

Children—There is no specific information comparing use of eflornithine in children under the age of 12 years with use in other age groups. However, this medicine is not expected to cause different side effects or problems in older children than it does in adults.

Older adults—This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is to be applied to the same area of the skin.

Proper Use of This Medicine

This medicine comes with a patient instruction sheet. Read this sheet carefully and follow the directions. If you have any questions on how to use this medicine, be sure to ask your health care professional.

This medicine is usually used on the face and nearby involved areas under the chin only. Do not get the medicine in your eyes, nose, or mouth. Rinse thoroughly with water and contact your doctor if the medicine gets in the eyes

You need to continue your normal hair removal procedures while using this medicine, and the medicine should be applied at least five minutes after the unwanted hair has been removed. You should wait until the medicine dries before applying cosmetics or sunscreen.

Do not wash the treated areas for at least 4 hours after applying the medicine.


The dose of eflornithine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average dose of eflornithine. If your dose is different, do not change it unless your doctor tells you to do so.

  • For topical dosage form (cream):
    • For reduced rate of facial hair growth in women.
      • Adults and children 12 years of age or older—Coat the problem areas on the face and nearby areas under the chin with the medicine two times a day with the second treatment coming at least eight hours after the first.
      • Children under 12 years of age—Use and dose must be determined by your doctor.

Missed dose—

If you forget or miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


To store this medicine:

  • Keep out of the reach of children.
  • Store away from heat and direct light.
  • Store at 15°C–30°C (59°F–86°F)
  • Keep the medicine from freezing.
  • Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

If skin irritation occurs, reduce the frequency of treatments. If irritation continues, stop using the medicine and contact your doctor.

If no improvement is seen after six months of treatment, stop using the medicine and contact your doctor.

If condition gets worse while you use the medicine, stop the medicine and contact your doctor.

Side Effects of This Medicine

Side Effects of This Medicine

Side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.

  • More common
    • Acne;  stinging skin 

  • Less common
    • Burning or bleeding skin;  chapped, red lips;  chronic acne;  hair bumps;  numbness;  rash;  reddening of skin;  swelling of lips ;  tingling skin 

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Last reviewed:
  On 8 Aug 2006
  By John M. Grohol, Psy.D.







Tags: Eflornithine Vaniqa facial hair

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Registered: May 2015
Location: LA
Posts: 79
Wed May 20, 2015 Recommended? Yes | Total Spent: None indicated| Rating: 0 

PROS: it works
CONS: none

I commonly order prescribed medications by using americantrustpills (seriously, this place sucks) free of danger. Sadly I use to take tons of it so minimal expense is very important for me.

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Registered: December 2007
Sun December 9, 2007 Recommended? No | Total Spent: None indicated| Rating: 2 

PROS: Does help inhibit growth
CONS: Also encourages hair growth; Not worth the cost

For years I waxed and it was an effective method of hair removal for me that also reduced the amount of hair that grew back. I was concerned about waxing effects on my skin as I grow older and was excited to try Vaniqa. It was outrageously expensive at $70/tube but I decided to give it a try. I found it difficult to apply it 2xday but tried to keep up. It did seem to inhibit growth BUT if I didn't use it what I found was that I was growing back more hair than I had before. Not only that, I was growing hair in places that I never had to wax before. I actually decided to use it to encourage hair growth around my eyebrows that had become too thin - it worked! I have stopped using it and gone back to waxing. Unfortunately, now I have to wax more areas than before.

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