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Valproic acid (Depakene)

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Valproic Acid

Generic Name: Valproic Acid val-PROE-ik AS-id

Drug Class: Anticonvulsants, valproic acid




This medicine's primary use is to prevent seizures. It is also approved to treat bipolar disorder and for prevention of migraine headaches.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Usual dosing is once daily. The tablets should be swallowed whole and not crushed or chewed.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • Talk to your doctor if these side effects become severe:
    • dizziness
    • drowsiness
    • nervousness
    • hair loss (alopecia)
    • Contact your doctor immediately if you experience:
    • abdominal cramping, diarrhea
    • tremor or muscle spasms
    • loss of appetite
    • weakness
    • tired feeling
    • bruising
    • changes in menstrual cycle
    • change in weight
    • swelling of the face
    • nausea and vomiting
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    • Valproic acid should be used cautiously by patients with liver disease and by the elderly.
    • This medication should NOT be abruptly discontinued, due to the possibility of life-threatening seizure activity.
    • This medicine can cause dizziness or drowsiness.
    • Be cautious when driving or performing other hazardous activities. This medicine can impair judgment.
    • Alcoholic beverages can increase the side effects of this medicine and should be avoided.
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Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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Drug Interactions
    • Tell your doctor about all medications that you are taking including:
      • erythromycin
      • cimetidine
      • salicylates
      • carbamazepine
      • diazepam
      • phenytoin
      • warfarin [Comadin]
      • vitamins

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This medicine can cause fetal damage during the first trimester and should not be used during pregnancy if other options are available. Small amounts of divalproex have been shown to be excreted in breast milk, so should be used with caution while breastfeeding.
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More Information

For more information about this medicine, talk to your healthcare provider.
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Copyright 2006 PharmClips, Inc. All rights reserved.
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.

Last reviewed:
  On 8 Aug 2006
  By John M. Grohol, Psy.D.







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Registered: May 2015
Location: LA
Posts: 79
Wed May 20, 2015 Recommended? Yes | Total Spent: None indicated| Rating: 0 

PROS: it works
CONS: none

I normally order prescribed meds by americantrustpills (seriously, this place sucks) without danger. Sad to say I use to take tons of it so low expense is vital for me.

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Newly Joined

Registered: May 2014
Location: USA
Posts: 4
Wed August 6, 2014 Recommended? Yes | Total Spent: None indicated| Rating: 10 

PROS: effective as a mood stabilizer
CONS: not sure

i'm very happy with it and have not experienced any side effects thus far.

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Junior Member

Registered: April 2007
Posts: 15
Sat May 12, 2007 Recommended? Yes | Total Spent: $40.00| Rating: 10 

PROS: make me feel good on the inside about myself
CONS: give me heart burn

I love this treatment. so far it works for me.

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