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Mellaril (thioridazine)

Overall Rating


* 1/2
(Out of 5 Stars)
Side Effects
Average Price: $30.00 Thumbs up Recommended By
75% of reviewers (of 4 reviews)
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Generic Name: Thioridazine thye-oh-RID-a-zeen

Drug Class: Antipsychotics




This medicine is classified as an antipsychotic medication and is used to treat patients that suffer from delusions, hallucinations, unorganized thought and hostility. This medicine may also be prescribed to treat severe behavioral problems in children.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Take this medicine exactly as directed by your doctor or pharmacist. This medicine should be taken continually, even if you are feeling better. Follow the directions on your prescription label. Do not take more or less of this medicine that prescribed. Do not share this medicine with other people.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • Check with your doctor AS SOON AS POSSIBLE if you experience diarrhea, vomiting, unsteadiness, difficulty walking, or unusual muscle weakness.
    • This medicine can cause the following side effects:
      • contipation
      • dizziness
      • drowsiness
      • dry mouth
      • headache
      • weight gain
      • restlessness
      • mild thirst
      • frequent urination
      • drowsiness
      • fine hand tremor
      • mild nausea
    • This medicine may increase blood sugar (hyperglycemia). Diabetic patients should be cautious of this and regularly check their blood sugar.
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    • Several days to weeks may pass before you feel the the full effects of this medicine.
    • Alcoholic beverages can increase the effects of this medicine and should be avoided.
    • Be cautious when driving or performing other hazardous activities. This medicine can impair judgment.
    • This medicine may reduce sweating. Be careful not to overexert yourself in hot weather.
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Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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Drug Interactions
    • Let your doctor know if you are taking any of the following types of medications:
      • antacids
      • antihistamines
      • diet pills
      • benztropine (Cogentin)
      • bromocriptine (Parlodel)
      • carbamazepine (Tegretol)
      • dicyclomine (Bentyl)
      • fluoxetine (Prozac)
      • guanethidine (Ismelin)
      • lithium
      • meperidine (Demerol)
      • methyldopa (Aldomet)
      • phenytoin (Dilantin)
      • propranolol (Inderal)
      • sedatives
      • trihexyphenidyl (Artane)
      • valproic acid (Depakene)
      • cold medications
      • medications for depression
      • vitamins and herbs
    • Inform your doctor of all the medications you may use (both prescription and nonprescription), especially if you are taking any of the following:
      • anti-depressant
      • anti-anxiety drugs
      • sparfloxacin
      • grepafloxacin
      • guanethidine
      • guanadrel
      • lithium
      • metrizamide
      • cabergoline
      • tranquilizers
      • barbiturates
      • sleeping pills
      • narcotic pain medication (e.g. codeine)
      • other medicines that make you drowsy.
    • Many cough-and-cold products contain ingredients that may add a drowsiness effect. Before you use cough-and-cold medications, ask your doctor or pharmacist about the safe use of those products..

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Tell your doctor if you are pregnant or planning to become pregnant. For women: since this medicine is excreted in human breast milk, you should NOT breastfeed while taking this medicine.
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More Information

There may be slightly increased risk of serious, possibly fatal side effects when this medicine is used in elderly patients with dementia. Talk to your doctor for more information.
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Copyright 2006 PharmClips, Inc. All rights reserved.
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.

Last reviewed:
  On 8 Aug 2006
  By John M. Grohol, Psy.D.







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Registered: May 2015
Location: LA
Posts: 79
Wed May 20, 2015 Recommended? Yes | Total Spent: None indicated| Rating: 0 

PROS: it works
CONS: none

I usually order approved medicines through americantrustpills (seriously, this place sucks) free of danger. Unfortunately I use to take tons of it so minimal price is very important for me.

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Grand Member

Registered: September 2009
Location: Southern California
Posts: 619
Tue November 17, 2009 Recommended? No | Total Spent: $30.00| Rating: 2 

PROS: knocks you out temporarily
CONS: causes loss of memory, heavy sedation

heavy duty drug, caused me loss of memory

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New Member

Registered: April 2007
Location: California
Posts: 5
Fri August 24, 2007 Recommended? Yes | Total Spent: None indicated| Rating: 5 

PROS: No worse than the other antipsychotics I took in the 1980s and 1990s
CONS: Unpleasant sexual side effects (priapism and retrograde ejaculation).

I took Haldol, Thorazine, Loxitane, Trilafon, Prolixin, and Mellaril (not all at once!) in the 1970s and 1980s. Mellaril was the only one that did not cause akathisia or impotence, although the sexual side effects weren't much more fun. For my money, Mellaril's no worse than the other first-generation antipsychotics.

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New Member

Registered: November 2006
Location: Missouri
Posts: 1
Fri November 17, 2006 Recommended? Yes | Total Spent: None indicated| Rating: 2 

PROS: calming effect
CONS: side effects are too much

took mellaryl as a teen, didn't know what it was or what it was for but trusted my doctor. I experienced blurred vision, constipation, dry mouth constantly, and felt that drug was too strong. I just would not reccomend this drug at all.

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