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Cymbalta (duloxotine hydrochloride)

Overall Rating
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2.88
Rating:

2.88

***
(Out of 5 Stars)
Side Effects
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2.19
Pricing
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3.03
Average Price: $17.27 Thumbs up Recommended By
61% of reviewers (of 49 reviews)
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Cymbaltaź

Generic Name: Duloxetine hydrochloride

Drug Class: Antidepressant, SSNRI

 

Contents

 

Description
This medicine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). This medicine is used to treat depression. This medicine is also used for nerve pain (peripheral neuropathy) in diabetic patients. Your doctor may prescribe this medicine to treat other conditions.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Follow the directions printed on your prescription label. Ask you doctor or pharmacist if you have any questions about how to take this medicine. This medicine should be taken by mouth. This medicine should be swallowed whole and should not be chewed or crushed, nor should the contents be sprinkled on food or mixed with liquids. All of these might affect the enteric coating. Do not quickly stop this medicine without talking to your doctor.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • Talk to your doctor if these side effects are bothersome or do not go away:
      • nausea
      • drowsiness
      • dizziness
      • nervousness
      • insomnia
      • headache
      • increased sweating
      • lightheadedness
      • sexual problems
    • A few of the most common side effects with this medicine include:
    • nausea
    • dry mouth
    • constipation
    • fatigue
    • somnolence
    • increased sweating
    • If you experience other bothersome side effects, contact your health care provider.
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Warnings/Precautions
    • Patients and their families should be alert to personality changes such as increased agitation or talk of suicide.
    • Do NOT stop taking this medicine without first talking to your doctor.
    • Alcoholic beverages can increase the effects of this medicine and should be avoided.
    • This medicine may cause drowsiness or dizziness.
    • Before taking this medicine, notify your doctor if you have:
      • history of alcohol abuse
      • narrow-angled glaucoma
      • kidney problems
    • Patient should watch for worsening depression or suicidal tendencies. If you are feeling more agitated, talk to your health care professional.
    • This medicine can cause dizziness or drowsiness.
    • Be cautious when driving or performing other hazardous activities.
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Overdose
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.
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Drug Interactions
    • Patients should be advised to inform their physicians if they are taking, or plan to take, any prescription or over-the-counter medications, since there is a potential for interactions.
    • If you are taking a group of medicine called "MAO inhibitors", they cannont be taken with this medicine. Stop the MAO inhibitor 14 days prior to starting this medicine. Your doctor or pharmacist can assist you with this.
    • Before taking any new medications, either prescription or over-the-counter (OTC), talk to your doctor or pharmacist about mixing medicines.
    • Avoid taking St. John's Wort with this medicine.

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Pregnancy/Nursing
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during therapy. Neonates exposed to SSRIs or SNRIs late in the third trimester have developed complications requiring prolonged hospitalization. (1) Nursing is not recommended while taking this medicine.
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More Information

For more information about this medicine, talk to your healthcare provider.
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Copyright © 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.
Last reviewed:
  On 8 Aug 2006
  By John M. Grohol, Psy.D.

 

2p107cymbalta.jpg

 

 

 

 

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Reviews
Anonymous
Review Date: Sat July 1, 2006 Would you recommend the product? Yes | Total Spent: $20.00| Rating: 7 

 
Pros: Adequate anti-depressant
Cons: Sexual side effects. Sleepiness.

It works well with mood stabilizers.

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alf0156
Member

Registered: August 2006
Posts: 59
Review Date: Thu August 31, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 9 

 
Pros: it works
Cons: bad stomic cramps if not taken with a small amount of food

it works

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alisandria
Veteran Member

Registered: August 2006
Location: USA
Posts: 303
Review Date: Fri September 8, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 6 

 
Pros: N/A
Cons: headache and agitation/anxiety

I tried this on two separate occassions with the hope I could get past the side effects, because I know it's also supposed to be good with neuropathic pain and hopefully would alleviate the pain I suffer. Thing is I could never get past the headaches I got. The second time I tried it I did manage to stay on for a month, but then just had to quit, I had migraines constantly and was experiencing more anxiety than prior to being on it (probably cause of the amount of pain I was in from migraines). Unfortunate because I know that this drug has worked well for many.

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Anonymous
Review Date: Wed September 13, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 6 

 
Pros: elevated my mood
Cons: felt more anxious, lost weight, nausia and supressed apetite and sex drive.

I was on it for one and half months and although I did feel better, I got more panick attacks, and I completely stopped eating and passed out a lot because my blood pressure dropped so low.

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dottie
Grand Poohbah

Registered: July 2005
Location: Ohio
Posts: 1526
Review Date: Thu September 14, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 9 

 
Pros: elevated my mood
Cons: bizarre dreming, nightmares, insomnia, headache, sinus congestion. Visual problems. Dry mouth,

I can't recommend this. Too many side effects. I have been on it for 2 years and the side effects seem to be worsening. Going to ask my doctor to change to another A-D. Groan.

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Xilber
Newly Joined

Registered: December 2006
Review Date: Fri December 1, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 2 

 
Pros: can't remember any
Cons: sleepiness, constipation

Was on it for a short while for depression. I was extremely tired all the time and constantly constipated.

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superwoman
New Member

Registered: December 2006
Posts: 4
Review Date: Wed December 6, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 3 

 
Pros: worked okayish at first
Cons: chronic insomnia, drowsiness,

Been on this med for 4 months. Felt better after about a week of being on it. It gave me some motivation to face my anxiety head on. The side effect of insomnia has not eased in all this time. Takes HOURS to get off to sleep then keep waking during the night. Very lethargic during the day. It seems to have now pooped out and my mood has dropped again. It helped my anxiety to a degree. I wouldn't recommend it because it's effects are not consistent.

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RollerCoaster
Newly Joined

Registered: December 2006
Review Date: Wed December 13, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 2 

 
Pros: Calming affect
Cons: Major daytime sleepiness, Sexual problems, Dry mouth

This is the second time I have tried this stuff. It made me so sleepy I thought there was something else wrong with me....constantly yawning and lethargic. It did have a calming effect - like I haven't a care in the world - and would be great if I wanted to lay around the house and sleep all the time, but I am (was/want to be again) a very active person and have work to get done. Although it did not reduce sexual drive, it made climax nearly impossible and even then, not satisfying. Since everyone is affected by these drugs differently, it is hard to make a recommendation....but if you are a physically, sexually active male who relies on being awake and alert for work, don't take this drug!

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bhill0821
Newly Joined

Registered: December 2006
Review Date: Sun December 17, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 9 

 
Pros: Great!! Really helps with my feelings
Cons: Side effects, but if you stay on it and take it regular, they subside

Wow, alot of negatives about this medicine. I have been on this medicine for about 2 years. It really works. I stopped taking it for a few weeks and noticed a big difference in my mood and was crying all the time about any little thing. If I have to take this med for the rest of my life, so be it. I am going to get through life on a day by day of dealing with ups and downs by taking the med and enjoying life.

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sallyoop
Newly Joined

Registered: December 2006
Review Date: Wed December 20, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 5 

 
Pros: the world literally seemed brighter
Cons: made me reckless

This medicine made me sleepy and worked wonders for the constant pain I was in due to my depression. I am not sure why I stopped it except that it seemed to worsen my anxiety and did not really help my depression.

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Anonymous
Review Date: Thu December 28, 2006 Would you recommend the product? Yes | Total Spent: $30.00| Rating: 9 

 
Pros: helps with nerve pain, self injury urges, and depression
Cons: none

This pill is a wonder drug. My psychiatrist and neurologist both reccomended it. It takes the place of 3 different perscriptions. I would reccomend it to anyone, especially if they have nerve pain!

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vanna123
Member

Registered: July 2005
Location: orange county
Posts: 296
Review Date: Sat January 27, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 6 

 
Pros: works well on the apin
Cons: weird dreams

had some sucess with the pain -- did not help much with the depression

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ladyprime
New Member

Registered: November 2005
Location: santa maria,ca
Posts: 3
Review Date: Mon January 29, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 0 

 
Pros: working well for me ..until...
Cons: none, really

until my MH nurse was a jerk and wouldnt give me full dosage to 'punish' me...then i went into a depresion, but out of it now. after reading all these comments, it appears to not work to well for people, but it has been great for me..ive been on wellbutrin 450mg ( this stuff saved my life) ive beenon buspars for about a year, that doing well too, and the cymbalta for about 3-4 months...finally got my little'cocktail'correct

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SecretAngel
Newly Joined

Registered: January 2007
Location: United States
Review Date: Fri February 2, 2007 Would you recommend the product? No | Total Spent: $4.00| Rating: 1 

 
Pros: None
Cons: Horrible side effects when starting

When I started this medication I was so sick for the first week that I could barely get out of bed. I had a horrible headache, and my stomach was so upset that I was not eating or drinking. Eventually it got so bad that I was admitted to the hospital for dehydration.

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Pomegranate
Poohbah

Registered: February 2007
Location: Chicago area
Posts: 1321
Review Date: Mon February 5, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Pros: helped daily pain
Cons: episodes of heavy sweating or hot flashes

I was on Zoloft for major depression and anxiety for several years. But I suffered from joint, muscle and nerve pain daily, most often moderate, sometimes very bad. Switching to Cymbalta helped with the daily moderate pain in legs, upper spine and joints. The very bad lower back and joint pain was not affected but does not occur as often, so it brought me much pain relief along with the same relief from depression as the Zoloft gave me.
With the Zoloft I had no side effects after the first two months. With Cymblata the only side effect I have is hot flashes, a couple or so a day. Well worth the pain (and depression) relief to me.

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MoodyOne
Newly Joined

Registered: April 2007
Review Date: Wed April 18, 2007 Would you recommend the product? Yes | Total Spent: $0.86| Rating: 10 

 
Pros:
Cons: None so far

Cymbalta Smile I LOVE Cymbalta! This has been a miracle drug for me. I was already taking 100mg of Lamictal once per day when I initially started taking Cymbalta. I immediately started having some side effects including dry mouth, nausea, irregular heart beats and decreased appetite. However, my moods were so dramatically improved that I decided to wait it out. After about 10 days the side effects (all but the decreased appetite) went away. When people used to tell me that life wasn't that bad I never believed them. I can breathe now and I feel wonderful in my own skin. I used to break down crying at trivial things. As an added bonus I have lost 14 pounds! Yes, I am a Cymbalta cheerleader, but I do know that this is not for everyone. The docs had me on countless SSRI's before they tried this and none of them ever worked. In fact, they made my condition much, much worse. I hope this helps someone.

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jimmyjetta
Newly Joined

Registered: May 2007
Review Date: Sun May 13, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Pros: none
Cons: migraines? feeling generally miserable.

Cymbalta is the only antidepressant I've taken to leave me feeling constantly awful. The only way I can describe it is as a coffee-buzz-gone-out-of-control with effects similar to some migraines (BTW, watch the espresso intake while on this drug: I experienced heart palpitations, sweats, and even worse than normal symptoms after coffee one evening).

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adamsmom
Newly Joined

Registered: July 2007
Review Date: Wed July 11, 2007 Would you recommend the product? No | Total Spent: $25.00| Rating: 2 

 
Pros: none
Cons: did not work at all for me

I was more depressed when taking this than I was before I took it.

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xp1155
Member

Registered: August 2007
Location: Ohio
Posts: 30
Review Date: Sun August 26, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 7 

 
Pros: helps physical symptoms, side effects were mild
Cons: mania, dry mouth

This product was awesome at treating my physical symptoms of depression. I am in pain almost every day of my life and, with this drug, I was almost pain free. The dry mouth I had was tolerable. However, it did cause mania and I was not able to sleep. I think I might try it again with a mood stabilizer. If you suffer from physical symptoms of depression, or generalized pain, I highly encourage you to consider this treatment with your doctor.

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Prada
Member

Registered: August 2007
Location: Salt Lake City, Utah, USA
Posts: 26
Review Date: Fri September 14, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Pros: Took all my depression and anger away.
Cons: Made me VERY anxious. Was on Neurontin to counter this.

It worked wonders for me. If it weren't for the price I would still be on it. The only problem was the anxiety it caused, I couldnt sit still no matter what dose I was on. They had me on Neurontin(800mg a day)to try to counter it though that only helped for the first 3 weeks.

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bellestar
Junior Member

Registered: September 2007
Location: NC
Posts: 8
Review Date: Wed September 19, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Pros: was able to hold my water better
Cons: withdrawal

After four months, it just stopped working. It wasn't doing much good to start with as far as mood. THE worst part is withdrawal. I started in May and I'm still titrating down. I had to break open the caps and count pieces....every time I step down a few, I cry for two days off and on. I'm down to 8 little pieces a day...I'll do that for two weeks and then go to five or six.
NO WONDER they say you can be suicidal after taking this and then coming off....so, moral of my story....if you ever take this and need to get off, go as slowly as possible, break open the caps and do not follow the Dr's orders according to the drug maker. The lowest dose is 20mg....I probably take .005 mg at this point and still boo-hoo and get headaches.
IMO...it shouldn't be sold at all.

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102riley
New Member

Registered: October 2007
Location: Southeast Alabama
Posts: 3
Review Date: Wed October 10, 2007 Would you recommend the product? Yes | Total Spent: $23.00| Rating: 6 

 
Pros: no serious side effects and I think I am doing a little better
Cons: itchy, I started ichying three weeks after taking it

I have not been very pleased with this treatment. I do think it was a better addition to my mood stabalizers than the SSRS, which seem to get me going very fast with suicidal thoughts.

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biplr4me
Junior Member

Registered: July 2007
Location: Waukesha, WI
Posts: 8
Review Date: Thu October 18, 2007 Would you recommend the product? Yes | Total Spent: $0.25| Rating: 8 

 
Pros: Lightened mood, clearer thinking
Cons: Possibly building a tolarance to it

I was placed on it to help my mood and ADHD. Worked well until now. I went up on the dosage 120mg per day and it only seems like my mood is flat, but my ADHD is still under control. Although to be fair I have been going through a very emotional time so that may be overwhelming to its effects. Total time on it is about 2 years and I do still get a headache now and then but most side effects are manageable. Overall I think it's a good med to use but I still have my questions on tolerance of it.*UPDATE* 05/01/08 I am now off it completely. It seemed to lose It's use for me. It was also suppressing my emotions. I do feel more up being off of it. It was a good med until I hit that wall of it no longer doing it's job. The weight loss is nice also being off of it. It may work for some but it stopped for me.

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mazer
Member

Registered: January 2008
Location: in my own crazy world
Posts: 20
Review Date: Wed January 2, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Pros: worked at first and also free in UK
Cons: heart racing when take it,dont take it a night

I have been on this for a year now,got told by pdoc to take it in the morning as it affects your sleep,ie keeps you awake,it is ok at first for depression but wears off quick,if you forget to take a dose I get head zaps ! weight increase too,Im now coming off this as its not working anymore

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sarcasticme
New Member

Registered: January 2008
Location: North Carolina
Posts: 1
Review Date: Sat January 26, 2008 Would you recommend the product? No | Total Spent: $0.67| Rating: 1 

 
Pros: None
Cons: Took this for about two weeks, caused so much pain that it worsened the depression!

I couldn't handle the side effects. They caused me a great deal of pain, which doesn't help depression at all!

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djmojo
Newly Joined

Registered: February 2008
Review Date: Sat February 16, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Pros: Don't know, was mega dosed by my pdoc!!!
Cons: total lack of care, bills, job, wife and kids.

Drink alcohol and be prepared to suffer like never before Getting off after a year was a real mother sleepy,dull, heavy reactions.....but hey! Ilost weight! jeez My anxiety was off the scale, eating xanax like candy

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vulnerome
Member

Registered: October 2004
Location: Mongolia
Posts: 119
Review Date: Sun February 17, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 4 

 
Pros: Numbness.
Cons: Numbness, made me very tired.

I was put on this in addition to Mirtazapine. It just made me more and more numb to the point that I no longer felt love for my boyfriend. Nor did I feel anxiety or annoyance when he vanished for two weeks, or happiness when he returned. Put simply, I did not care about anything. It was more like a chemical frontal lobotomy than anything else. My therapist felt it was seriously hampering progress. The numbness could be a useful respite to some people though, and I would consider taking it again for that purpose if some major trauma came into my life.
Coming off it now and seem to be getting withdrawals despite only being on it a month - trouble with visual tracking, dizziness, jolty feelings in my body, brain zaps, skin crawling, night jerking, weird arse dreams etc. Quite enjoying the weird effects myself Smile but they might upset some people.

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petuniacat
Newly Joined

Registered: February 2008
Review Date: Mon March 3, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 10 

 
Pros: wakes you right up, keeps you positive
Cons: hard time going to sleep

This medication works wonders for me. I am normal what ever normal is. As long as I function at work I'm happy.

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thancen
Junior Member

Registered: March 2008
Location: Texas
Posts: 8
Review Date: Thu March 6, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 6 

 
Pros: works well with Depakote
Cons: Excessive diahrea

works excellent with Depakote and my mood was more stable, but I had the worse diahrea of my life. Even with anti-diahrea medicine the side effect didn't ease. I had to go on a diet of rice and jello. Couldn't live eating like that forever.

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Anonymous
Review Date: Sun March 16, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 5 

 
Pros: decreased appetite
Cons: fatigue, feeling a bit "foggy"

I've only been taking this for four days, but so far I don't have any complaints. I'll probably be posting in a week or two with an update. I listed the decreased appetite as a "pro", because I'm 50 pounds overweight, so I'm not complaining about that.

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mazer
Member

Registered: January 2008
Location: in my own crazy world
Posts: 20
Review Date: Sun April 6, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 0 

 
Pros: none
Cons: makes you feel shit

should be banned as its awful to come off,been on it for over 2 years and cant get off this poison !

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TaintedGoth1
Grand Member

Registered: April 2008
Location: PA, USA
Posts: 959
Review Date: Sun April 6, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Pros: Excellent for depression
Cons: Wears off too soon

I really would recommend this. I've not had the side effects noted by others and do extremely well on this medication. Take it midday as sometimes it does not have the same potency in the evening if you take it in the morning.

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_Hope_
Grand Poohbah

Registered: September 2007
Location: MA
Posts: 1803
Review Date: Mon April 7, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 3 

 
Pros: none yet
Cons: sexual problems , dehydration, constipation

I have only been on it 2 weeks , I havenot noticied anything good yet , but the worst is an inability to orgasm, that doesn't help my depression much

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katfriendly
Junior Member

Registered: April 2008
Location: OHIO
Posts: 6
Review Date: Sat April 26, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 10 

 
Pros: This has kept my deep depressions to a minimum.
Cons: When I first started on Cymbalta, had minor accidents (bathroom, i mean).

This antidepressant has worked better for me than any other, and believe me, I think that I have tried most of them.

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OMGthathurts
Newly Joined

Registered: June 2008
Location: Tulsa, Oklahoma
Review Date: Sat June 14, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 6 

 
Pros: I felt better than I had in years, really seemed to do the trick
Cons: sweating

I felt better than I had in years, and it helped plantar fasciitis, urinary incontinence as well as my depression. I had so many hot flashes, my scrubs were soaked, and my face was red all the time. Eventually it stopped working on the depression. Now in weaning off, I'm having strange electrical type shocks in my brain and body, I am crying a lot and had about a week of nausea. This is much worse than the depression itself, and when I tried to go back on full strength again, it didn't work. I am miserable. Trying to take Welbutrin now, I already take clonazapam for night terrors.

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emi24
Newly Joined

Registered: June 2008
Review Date: Sun June 22, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Pros: helped with anxiety and TMJ problems
Cons: slight nausea and insomnia for the first week or so but not too bad

i was such an i-don't-believe-in-western-medicine-especially-anti-depressants type person but i tried cymbalta after my doc highly recommended it. i was hesitant but tried it as a last resort as i am dealing with chronic neck pain, TMJ, and fatigue which was causing severe depression and anxiety. i had even tried effexor for 6 weeks before which is a similar drug but experienced several side effects. cymbalta has not banished my physical ailments but has allowed me to focus on other things and not so much on the pain. i was in so much pain i could not even function. now, i am able to. the pain is still there but the anxiety about the pain is gone as well as the major depression. i feel like it just gives me better coping skills or something. i'm not saying its a permanent fix but until i get whatever it is going on resolved, cymblata helps me deal with it in the meantime. i have no side effects yet and it has been 4 weeks. i started to feel better after only 6 days which is faster than most SSRIs and SNRIs. i just wanted to give cymbalta a fighting chance because there are so many negative things said about it. it may not be for you because its different for everyone but i'm telling you...for the time being it has saved my life. give it a chance!

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MyCatPete
New Member

Registered: June 2008
Posts: 2
Review Date: Tue June 24, 2008 Would you recommend the product? Yes | Total Spent: $0.70| Rating: 9 

 
Pros: Less anxiety, better sleep
Cons: Side effects hard to overcome at first

I started out on 30mg to help with depression/anxiety. The side effects were very hard to overcome at first - I was extremely tired, constantly yawning, sweating easily, and experienced nausea. My doctor increased my dosage to 60mg after one month. My side effects also increased, but I also noticed many positive results. I haven't had a panic attack in several months, my depression has eased, and my appetite is back to normal. I have been taking Cymbalta for 7 months and am so far pleased with the results.

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jen29
Member

Registered: June 2008
Location: Wisconsin
Posts: 82
Review Date: Tue July 1, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Pros: Extremly helpful with depression
Cons: Only FDA approved for 60 mg, so Insurance won't cover it with I need a boost.

I have been taking cymbalta since it first came out, about 2 or 3 years. It works great when I take it. If I miss just one dose I get the worst headache. It does go away about 4 hours after I take it again. My doc. wants to put my one 120 mg, but having problem with ins. co.

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trillian
Newly Joined

Registered: July 2008
Review Date: Fri July 11, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 7 

 
Pros: i feel much better
Cons: dry mouth, night sweats, pounding heart, aggitated feeling, makes my skin crawl

well i am still taking it. haven't been on it long. hoping some side effects go away but the ones i have are bareable compared to the prozac manic episode that cost me 3,000 dollars. trying tranzene to counter-act the agitation.

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Is4110
New Member

Registered: May 2008
Location: SW Arkansas
Posts: 5
Review Date: Thu July 17, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 4 

 
Pros: Relieved depression.
Cons: Side effects.

I only took it once and it totally spaced me out. Plus, I couldn't urinate! No joke..when I went to the toilet, I would sit there for 2-3 minutes waiting for the message from my brain to reach my bladder to release the urine. I'm not kidding. It was like I had no control over my bodily function! Glad I didn't stay on it!!

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runnergrrl
New Member

Registered: January 2008
Posts: 4
Review Date: Mon July 21, 2008 Would you recommend the product? No | Total Spent: $35.00| Rating: 3 

 
Pros: decreased depression and suicidal thoughts
Cons: Problems urinating at night, headaches, tiredness, dry mouth

Started taking Cymbalta in June of '08. Got up to 60 mgs. Felt great at first but, have side effects from it. Biggest problem is getting up several times a night to urinate, but can't do it. Starts around 4 am and does not stop until I get up for the day. Extreme tiredness due to this problem. Dry mouth is a problem too. Overall, this drug is ok. But, dreading hearing about the withdrawal symptoms after experiencing them with Effexor.
I cut cold turkey at 60 mgs only being on the drug for less than a month.
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Day 3 of withdrawal from Cymbalta. Mind you I was only on this drug for 24 days. I have been through the Effexor (after being on it for almost 2 years at 150mg) withdrawal and thought that this withdrawal would be a picnic. I can't believe how terrible the past 3 days have been. I have been extremely dizzy, brain zaps, cold sweats, and peeing all the time (I think this is due to the fact that I had urinary problems with Cymbalta and now that it is getting out of my system, I am able to urinate again - kinda scary knowing this). I hope that day 4 proves to be like it was when I was going through with the Effexor withdrawal. I started to feel better then. But, who knows. Cymbalta doesn't mess around.
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Day 6 of withdrawal from Cymbalta. Feel much better, though still have weird brain zaps and a little bit of vertigo. But, I started to drink green tea and have been drinking lots of fluids the past few days. I definitely feel much better today than six days ago. I was lucky I did not have work and could lay in a dark room with the air conditioning on for a week.
*It will be different for a lot of people due to various reasons like dosage amount, length of time on medication... I got off of Effexor in six days, so my metabolism must be faster than others.

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trillian
Newly Joined

Registered: July 2008
Review Date: Tue July 22, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 0 

 
Pros: made me happy
Cons: made me manic, night sweats, brought back addictions, bad withdrawals even if weening off, don't care about anything

well, seemed alright at first, but got to the point i was tired i went home and read all afternoon until bed. but when i went to bed, couldn't sleep. i didn't care about doing housework, my performance at my job suffered cause i just didn't care and didn't fell like doing anything. as with prozac, i picked up my old addictions that i have been clean from for almost three years. all in all, i lost $5,000 to my addictions while the doctor tried to find the right anti-depressant. i went from functional but moody and agitated to not-functional. i'm done trying, my family, my checkbook, my life can not go through "trying" another anti-depressant. even if you ween off it, the withdrawals are awful, joint pain, headaches, nausea, constant crying.

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retrobaby
Newly Joined

Registered: July 2008
Review Date: Thu July 31, 2008 Would you recommend the product? Yes | Total Spent: $15.00| Rating: 4 

 
Pros: Hmmm, not crying
Cons: sweat like a pig!! can't sleep at night (2:30a.m., here I am), constipaaaation.

I've been on this since it became available at various doses. Doc switched from Wellbutrin/Lexapro to Cymbalta simply in the hope it would aid in pain relief & help depression(remained on Lexapro). I don't know ..... I miss my Wellbutrin. At 120mg I ended up in the ER w/tachycardia. Weaned off Lexapro, then down to 30mg on Cymbalta, couldn't stop crying, again-miss my Wellbutrin.... but I could poo! On 60mg now for a couple months, think I've hit a wall, can't sleep even tho Lyrica makes me weary .... better suck down my Ambien. Is there a maybe recommendation?

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Taonuviel
Poohbah

Registered: May 2004
Location: Michigan
Posts: 1272
Review Date: Fri August 22, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Pros: None
Cons: Withdrawal is Hell. Dangerous. Often leaves you with a strange feeling of illness/weakness.

This stuff's so bad, I hope some lawsuit will come out against Lilly so I can join. Evil greedy poisonous monsters... Find out for yourself, search "Cymbalta withdrawal".

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lavitsef
Newly Joined

Registered: March 2009
Posts: 1
Review Date: Sun March 8, 2009 Would you recommend the product? Yes | Total Spent: $20.00| Rating: 9 

 
Pros: it works and relieved leg cramps
Cons: occasional mild dizzy

Went from Prozac forever to Cymbalta. I had leg cramping and tight leg muscles. Cymbalta 60 mg stopped the leg tightness and works well for mild depression. Good product

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Richardinvegas
Newly Joined

Registered: March 2009
Posts: 1
Review Date: Thu March 19, 2009 Would you recommend the product? Yes | Total Spent: $50.00| Rating: 9 

 
Pros: Stablized my moods
Cons: None, yet

I have been on cymbalta (after Effexor XP) for over a year and it is, so far, my miracle drug. I don't get my highs and lows in depression/anxiety and I am lucky not to have any side effects that I have noticed. I am much happier in life on it. One exception...I am still havind difficulty coping with people...they just don't get me!!?? I try to be liked, but I constantly fail. Thanks you Cymbalta

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essential
Junior Member

Registered: June 2009
Posts: 17
Review Date: Fri July 10, 2009 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 9 

 
Pros: works
Cons: made me manic, night sweats, brought back addictions

if you ever used to buy cymbalta fro your needs you will be doing it for a long. Good product buy hard on withdrawal!

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CRW60088
Newly Joined

Registered: September 2009
Posts: 2
Review Date: Wed September 2, 2009 Would you recommend the product? No | Total Spent: None indicated| Rating: 4 

 
Pros: thoughts were clearer
Cons: major side effects

I first had trouble sleeping, so my dose was lowered until I got use to it. Then I had abdominal pain, and tar like stools. Very painful to pass. I had a colonscopy and an endoscopy. I'm 32. It wasn't pleasant. After these were cleared, I started having sharp pains in one breast, then I started to leak. I thought it was puss, but later found out it was milk. I have never been pregnant, I found it quite scary, and the doctors thought I had breast cancer. Got tested, no cancer~!!! yeah!! Got off Cymbalta and all the symptoms went away. The doctor's never looked at these issues as side effects even though it was my only new prescription. My doctor said the medication was tested on men, so leakage wasn't a issue.

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psychodwnldr
New Member

Registered: October 2009
Location: maryland
Posts: 3
Review Date: Sat October 17, 2009 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 10 

 
Pros: controlls my anger & moodswings
Cons: none that i can tell

my doctor put me on cymbalta back in augest of this year for my anger and mood swings. best thing thats happened. my wife & childern noticed a major difference in my behavior the 1st day i was one it. i've been diagnosed w/cyclothymic personality disorder i started out on 30mg then bumped to 60mg now i take 120mg. from 1st day i started i've been full of energy,maybe a little too much.3am i'm still wide awake wanting to do thing around the house.if im lucky i get 4 hrs sleep but still bursting w/energy next day.it works for me

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